In a Scientific Opinion published on 10 January 2018, EFSA updated the Tolerable Daily Intake (TDI) for 3-MCPD.

In 2016, EFSA first assessed the potential risks of 3-MCPD and glycidyl esters of the fatty acids in 2016.

EFSA concluded that glycidyl esters were genotoxic and carcinogenic compounds which means that they can damage DNA and cause cancer.

EFSA decided to re-examine its 2016 assessment following the publication by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) of a different TDI than their 2016 assessment (TDI established by JECFA: 4µg/kg bw).

The method used by EFSA to calculate the originally provided TDI was updated with a new approach called benchmark dose (BMD).

This re-evaluation established a TDI of 2 µg/kg bw closer to the TDI established by JECFA.

EFSA and JECFA used the same toxicological data but employed different techniques for dose benchmark modelling.

Despite these technical differences, the two organizations reached the same general conclusions about the possible adverse effects of 3-MCPD and the level of public health concern.

The update concerns only 3-MCPD and its esters. The evaluation carried out for glycidyl esters has not been modified.

The laboratory is able to determine the content of 3-MCPD in plant products and infant milks. The analysis of soy sauce, hydrolysed vegetable proteins, tea, cocoa and infant milk can be carried out under accreditation.

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